A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn’t been helpful for many patients with metastatic colorectal cancer. In findings published in Clinical Cancer Research, the team identified specific proteins—fibronectin and …
Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO. Their study, published in the Journal for ImmunoTherapy of Cancer, shows t…
Mount Sinai researchers have developed a method to uncover the hidden immune cells that harbor the human immunodeficiency virus (HIV), a discovery that brings medical experts one step closer to a cure for the infection affecting nearly 40 million peopl…
Researchers conducting a clinical trial of immunotherapy drugs for people with head and neck squamous cell carcinomas (HNSCCs) found that patients responded better to a combination of two immunotherapies than patients who received just one immunotherap…
University of Virginia School of Medicine scientists have discovered how severe COVID-19 can destroy immune cells’ ability to repair the lungs, helping explain the lingering effects of long COVID. The findings suggest a new treatment approach for long …
A new study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children’s Hospital Los Angeles, shows evidence of dysfunction of the blood–brain barrier and inflammation in the central nervous system in individuals with Down syn…
Gut microbiota may be the key factor explaining why certain individuals do not respond well to the pneumococcal vaccine, a bacterium that can cause various diseases, such as pneumonia. This conclusion is drawn from a recent study led by the B Cell Biol…
Antibody treatment which activates the patient’s own immune system against cancer, known as immunotherapy, is increasingly being investigated as an alternative to chemotherapy and radiotherapy. This is because it specifically targets the cancer cells, …
In a recent study published in Science Advances, researchers led by Prof. Li Xinjian from the Institute of Biophysics of the Chinese Academy of Sciences have uncovered a novel immunoregulatory function of isocyanic acid (ICA), a reactive metabolite syn…
An international group of researchers has identified an important mechanism that enables stem cells to evade immune rejection. Their research, published in Nature, sheds light on how these specialized cells create an “immune-privileged” environment—are…
