BCG therapy—the gold standard treatment for non-muscle invasive bladder cancer (NMIBC), where the cancer has not penetrated the muscle layer—is one of the earliest forms of cancer immunotherapy. Now, 50 years after it was first developed from the tuber…
Biological drugs have improved the lives of many people with severe asthma. However, a new study from Karolinska Institutet in Sweden shows that some immune cells with high inflammatory potential are not completely eradicated after treatment.
For patients with recessive dystrophic epidermolysis bullosa (RDEB), a one-time surgical application of prademagene zamikeracel, an autologous COL7A1 gene-modified cellular sheet that is sutured onto a large, chronic RDEB wound, improves wound healing …
Mitochondria have primarily been known as the energy-producing components of cells. But scientists are increasingly discovering that these small organelles do much more than just power cells. They are also involved in immune functions such as controlli…
If spending time around dogs or cats makes your eyes water, your nose run, your skin itch or your breathing difficult, you’re not alone.
A University of Alberta research team has identified a DNA structure that activates the immune system in cancer cells that are usually resistant to immunotherapy, offering hope of new, more effective treatments for colorectal and other cancers.
Scientists at Nagoya University in Japan studied what happens when macrophages—a type of immune cell—encounter dying cancer cells in tumors and discovered a mechanism that accelerates tumor growth. When cancer cells begin to die within tumors, they exp…
The official results of the BRACELET-01 (PrECOG 0113) trial have been published in Clinical Cancer Research, detailing the safety and efficacy of pelareorep, an investigational oncolytic virus immunotherapy, when added to paclitaxel chemotherapy, both …
Colorectal cancer (CRC) is the second most common cause of death from cancer in the US and the most prevalent malignant tumor worldwide. CRC refers to cancer in the colon or rectum, the two parts that make up the large intestine. In the US, deaths from…
Neuroblastoma is a cancer that affects the sympathetic nervous system of children. It is unusual among cancers because it shows a range of outcomes: from aggressive, potentially fatal progression to a unique phenomenon where the tumor spontaneously reg…
