Your gas stove might be making your asthma worse: What you can do about it
We may think of air pollution as an outdoor problem, made up of car exhaust and smog. But if the air inside our homes is polluted, this can also affect our health.
Medical Xpress
Experimental mRNA cancer vaccine shows potential for advanced stage cancer patients in Phase I trial
Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.
Neoself-antigens found to induce autoimmune response in lupus
Autoimmune diseases are widespread and notoriously difficult to treat. In part, this is because why the immune system attacks its own tissues in patients with these conditions remains poorly understood.
Study finds ‘supercharging’ T cells with mitochondria enhances their antitumor activity
Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion. This phenomenon also hinders adoptive cell therapies, in which healthy, tumor-targetin…
Antibody-drug conjugate found effective against brain metastases in patients with HER2-positive breast cancer
A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. The findings, from an inter…
Antibodies in breast milk provide protection against common GI virus
A study led by researchers at the University of Rochester Medical Center found that breast milk provides protection against rotavirus, a common gastrointestinal disease that causes diarrhea, vomiting and fever in infants.
Indoor allergens worsen respiratory infections in children with asthma, study finds
Children with asthma who are exposed to high levels of indoor allergens, such as cockroach and mouse allergens, are at an increased risk of developing respiratory viral infections with symptoms, according to a new study by researchers at Dell Medical S…
Triple antibody therapy shows promise for long-lasting HIV control
In a study of 12 participants, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that a cocktail of three broadly neutralizing antibodies (bNAb) successfully suppressed virus in people living with HIV. A subset of participan…
Using molecular scissors to improve CAR-T cell therapy
Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients. This discovery has fueled new strategies that incorporate antibodies and gene editing to…
Gut microbiome found to influence location of immune cells
Researchers at the Experimental and Clinical Research Center of Max Delbrück Center and Charité—Universitätsmedizin Berlin (ECRC) have found that different anatomical sections of the gastrointestinal tracts of mice carry different compositions of micro…