Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, scientists assumed that blood production took place in t…
Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, researchers have used their knowledge of the immune system to develop therapies to treat or prevent diseases from influenza to aut…
Using an animal model of multiple sclerosis (MS), researchers have created a four-dimensional brain map that reveals how lesions similar to those seen in human MS form. These findings provide a window into the early disease state and could help identif…
Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis.
Brazilian researchers have developed a simple test that almost instantly tells whether a person has been exposed to any of the four dengue virus serotypes, as well as Zika virus. The test is an enzyme immunoassay similar to ELISA, a platform widely use…
For women with breast cancer, stressors are associated with deleterious alterations to the systemic and tumor immune environment, according to a study published online Feb. 14 in JAMA Network Open.
Four immunoassays for neurofilament light chain (NfL) demonstrate consistent performance in patients with amyotrophic lateral sclerosis (ALS), with high diagnostic and prognostic accuracy, according to a study published online Feb. 26 in Neurology.
A new study suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for traumatic brain injury (TBI). By studying the effects of the nasal anti-CD3 in a mouse model of TBI, researchers found the spray could …
Research reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice. This discovery could pave the way for a new class of drugs to treat rheumatoid arthritis, accord…
A study led by researchers at Mass General Brigham suggests a nasal spray developed to target neuroinflammation could one day be an effective treatment for traumatic brain injury (TBI). By studying the effects of the nasal anti-CD3 in a mouse model of …
