Discovery of immune-boosting fibroblasts offers hope for cancer patients
Southampton scientists working to improve survival for cancer patients have identified a key characteristic of the disease that could make treatment more effective.
Inmunología
Scientists develop ‘suspended animation’ technique for blood draws to aid research for underserved populations
Your blood is a delicate mixture. Researchers and clinicians often use blood to learn what’s going on inside our bodies, in part because siphoning off a tube of blood is easier and less painful than taking biopsies of an internal organ.
Novel screening tech enhances identification of cancer-targeting T cell receptors
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a new screening technology, Aptamer-based T Lymphocyte Activity Screening and SEQuencing (ATLAS-seq), to bett…
Scientists unveil surprising human vs mouse differences in a major cancer immunotherapy target
Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is significantly weaker than the human version, providing new info…
FDA approves subcutaneous opdivo qvantig for most solid tumor indications
The U.S. Food and Drug Administration has approved Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) injection for subcutaneous use for most previously approved adult, solid tumor Opdivo (nivolumab) indications.
Scientists unveil surprising human vs. mouse differences in a major cancer immunotherapy target
Since its discovery in the 1990s, programmed cell death protein 1 (PD-1) has been regarded as a leading target in cancer treatments. A checkpoint receptor that often resides on the surface of immune system cells, the PD-1 molecule works as a type of “o…
Novel class of anti-malaria antibodies could lead to next-generation interventions
A novel class of antibodies that binds to a previously untargeted portion of the malaria parasite could lead to new prevention methods, according to a study by researchers at the National Institutes of Health (NIH) published today in Science.
How a simple amino acid could shape immune response
A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response.
Targeting tristetraprolin in basophils: Researchers find promising therapeutic target for allergic inflammation
Inflammation is a crucial part of the body’s defense mechanism, playing a key role in fighting infections and repairing tissue damage. Basophils, a type of immune cell that makes up less than 1% of white blood cells, have recently emerged as critical p…
Targeting tristetraprolin in basophils: A breakthrough in allergic inflammation treatment
A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research shows that TTP controls the stability of mRNAs for inf…