In a new study, University of Arizona researchers created a model for cutaneous squamous cell carcinoma, a type of skin cancer, and identified two mutated tumor proteins, or neoantigens, that contain features of good candidates for a vaccine.
Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body’s ability to fight infection, new research shows.
Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment. But while they’…
Even small amounts of bisphenol A can lead to long-term health effects. When researchers studied adult rats exposed in the fetal stage, they found that females had developed a more masculine and males a more feminine gene expression pattern. This led t…
Melanoma is the most common form of skin cancer, but for patients with advanced melanoma who no longer respond to standard immunotherapy, treatment options are painfully limited. Vanderbilt researchers led by Professor Emerita of Pharmacology Ann Richm…
A new study has uncovered how a surprising player in the immune system, eosinophils, best known for their role in allergies and asthma, also helps protect the body against Candida albicans, one of the most common and dangerous fungal infections in humans.
A team of researchers led by Peter Mac’s Professor Sherene Loi has uncovered how having children and breastfeeding reduces a woman’s long-term risk of breast cancer.
Malaria remains one of the world’s most devastating infectious diseases, claiming more than half a million lives each year. In Africa, the illness is mostly caused by a parasite carried by mosquitoes—Plasmodium falciparum.
An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice while curbing previously encountered cytokine-relate…
Promising study in dual inhibition of PD1 and macrophage migration inhibitory factor
