An interdisciplinary team of scientists has developed a technology to decode immune cell communication. By measuring interactions between cells, the method offers insights into how the human body fights viral infections, how malfunctions can lead to au…
T-cell redirection therapy using chimeric antigen receptor (CAR) T cells and/or bispecific antibody (BsAb) has been established and become a promising treatment strategy for relapsed/refractory B-cell lymphomas. To further improve their therapeutic eff…
A new study meticulously sampled different lung regions in people with cystic fibrosis to understand why infections persist after new treatments.
Immunotherapy uses the body’s immune system to recognize and destroy cancer cells. One way to do this is through immune checkpoint inhibitors.
New research published in Nature has uncovered powerful evidence that may explain why a new chemical modification of RNA is made in cells.
Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.
A study published in Cell Reports Medicine reports a scalable, data-driven computational framework for designing combinatorial immunotherapies, offering hope for patients with poor responses to current immunotherapies.
For cancer- and infection-fighting T cells, glucose offers far more than a simple sugar rush.
In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin-converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer’s disease. Their …
It often starts with restless sleep. Mobility, swallowing, and speaking disorders are also typical. Yet a range of other symptoms make it difficult to diagnose anti-IgLON5 disease. Left untreated, this rare autoimmune disease leads to severe disabiliti…
