Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins—molecules that transport fat in blood—which enriches cancer cells with an antioxidant shield to survive stress, according to new research from Children’s Medical…
Scientists with the Fralin Biomedical Research Institute at VTC have created an engineered model of the supportive tissue found within a lymph node to study human health.
All of us produce a growth factor—called IL-15—which effectively protects us from cancers. Its role is to boost the production of immune cells that can rapidly detect and kill cancer cells when they first appear. One of these cell-types is appropriatel…
Inspired by advances in cancer therapy, a team at the Buck Institute has engineered immune cells equipped with specialized targeting devices called chimeric antigen receptors (CARs) that can distinguish and respond to tau tangles and various forms of t…
Primary sclerosing cholangitis, PSC in short, is a rare liver disease that destroys the bile ducts. It is a severe condition for which we currently have no effective treatments and often results in the patient requiring a liver transplant.
Why do people develop antibodies to food? While clinicians have long observed that healthy humans develop a particular type of antibody, called IgG, to the foods they eat, the reasons for this phenomenon have remained unknown.
Two studies suggest there is no significant benefit of early biologics over standard step-up care with methotrexate, but these did not select for poor prognosis. The aim, therefore, of the SPEED trial (Severe Psoriatic arthritis—Early intervEntion to c…
Glioblastoma (GBM) is the most aggressive and lethal form of brain cancer, with a median survival of only 15 months despite intensive treatment. Current therapies—including surgery, radiation, and chemotherapy—offer limited long-term benefit, and immun…
Scientists have discovered a unique class of small antibodies that are strongly protective against a wide range of SARS coronaviruses, including SARS-CoV-1 and numerous early and recent SARS-CoV-2 variants. The unique antibodies target an essential hig…
More than 40 million people worldwide are living with HIV-1, which continues to be a major global health challenge due to its ability to persist silently within immune cells, evading complete eradication. Researchers at LKS Faculty of Medicine, the Uni…
