Researchers at the Icahn School of Medicine at Mount Sinai have identified the mechanism of action of a treatment for small-cell lung cancer (SCLC), one of the most aggressive and difficult-to-treat cancers. Published this week in Cell Reports Medicine…
Structural Genomics Consortium researchers at The Neuro (Montreal Neurological Institute-Hospital) of McGill University, in collaboration with scientists from 11 major antibody manufacturers representing approximately 80% of global renewable antibody p…
Various forms of blood cancer exist—all of which are grouped together under the term leukemia. One common form of leukemia is acute myeloid leukemia (AML), characterized by a degradation of early blood cell precursors, i.e. stem cells and the precursor…
Researchers at NYU College of Dentistry and NYU Grossman School of Medicine are closer to understanding what drives the autoimmune disorder Sjögren’s disease, thanks to new discoveries about the role of calcium signaling, regulatory T cells, and interf…
At the beginning of the COVID-19 pandemic, numerous studies had shown that COVID-19 patients with high levels of neutrophils, a key immune cell, presented with more severe disease and poor clinical outcomes. It was not clearly understood how or why thi…
A new study shows how one kind of bacteria, Vibrio cholerae, triggers painful intestinal contractions by activating the immune system. The research also finds a more general explanation for how the gut rids itself of unwanted intruders, which could als…
Chimeric antigen receptor (CAR) T-cell therapy is a type of cancer immunotherapy where patients’ T-cells are collected and genetically modified to produce chimeric antigen receptors that recognize specific targets on cancer cells, allowing these T-cell…
Northwestern Medicine scientists have developed a method for identifying reactive cysteines on peptide antigens within the immune system, a development which may prove useful in cancer immunotherapy, according to a study published in Nature Communicati…
New research has explained how the body’s internal clock influences the inflammatory process of the immune system. The findings describe how immune cells, called macrophages, work differently at various times of the day and could pave the way for time-…
A research team from the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has identified a mechanistic link between high blood glucose levels and weakened immunity against viral infections in patients with type 2 diabetes (T2D). The coll…
