When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells also undergo metabolic reprog…
Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study focusing on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response …
A two-year follow-up clinical trial found that a new personalized cellular therapy treatment for relapsed or refractory B-cell lymphoma demonstrated strong safety and improved overall survival in patients, according to findings published in Blood.
The human cytomegalovirus, HCMV for short, lies dormant unnoticed in the body of most people for their entire lives. In immunocompromised individuals, however, the virus can cause life-threatening infections. It infects dendritic cells, a specific type…
A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic checkpoint in the function of tumo…
A recent study investigated the correlation between the specific anti-spike SARS-CoV-2 IgG immune response resulting from vaccination or previous infection, viral load, and fecal virus excretion, as well as their impact on the clinical characteristics …
Human herpesviruses comprise the alpha, beta, and gamma subfamilies and are a widely prevalent group of DNA-enveloped viruses capable of establishing lifelong latent infections in humans and causing various diseases. Among them, herpes simplex virus (H…
Researchers at the Technion’s Ruth and Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences have discovered a subset of blood cells that predict the success of immunotherapy treatment. These findin…
The American Academy of Otolaryngology–Head and Neck Surgery Foundation has published the Clinical Practice Guideline: Immunotherapy for Inhalant Allergy in Otolaryngology–Head and Neck Surgery. This clinical practice guideline identifies quality impro…
According to the National Institutes for Health, chronic sinusitis, also known as chronic rhinosinusitis (CRS), affects approximately 14.6% of the United States population and is currently the fifth most common condition treated with antibiotics, accou…
