When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell inherits different cellular components, which drive the cells toward divergent fates—one cell becomes a short-lived fighter called…
MOG antibody-associated disease (MOGAD) is a rare autoimmune disease of the central nervous system. The blood of patients contains antibodies against myelin oligodendrocyte glycoprotein (MOG), a protein in the myelin layer that surrounds the neurons in…
Researchers at The University of Texas MD Anderson Cancer Center have found that a mitochondrial enzyme, GFER, creates an immunosuppressive environment within pancreatic tumors, leading to treatment resistance.
Feeding babies peanut-containing foods as early as possible can help prevent peanut allergy, but a new study published in JAMA Network Open found that parents need more support to get it right. Interviews with parents revealed widespread confusion abou…
Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune responses.
Multiple sclerosis (MS) is a chronic autoimmune disease characterized by the disruption of nerve signals and various associated neurological symptoms, ranging from vision problems to numbness, weakness, fatigue and cognitive impairments. These symptoms…
Published today in Clinical Cancer Research, findings from a study led by investigators at the Vall d’Hebron Institute of Oncology (VHIO), which forms part of the Vall d’Hebron Campus, underscore the efficacy of analyzing circulating tumor DNA (ctDNA) …
Gut microbes may play a key role in training a mother’s immune system to adapt to the developing fetus during pregnancy, according to a preclinical study by Weill Cornell Medicine investigators.
EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy.
Antibody-based therapies are used to treat numerous diseases, from cancer to rheumatic disorders and multiple sclerosis. Antibodies recognize and bind to very specific structures. This allows them to direct active substances to exactly the right target…
