Primary Immunodeficiency Diseases with BCG-Induced Diseases: A 15-Year Longitudinal Cohort Study
J Clin Immunol. 2026 Feb 26. doi: 10.1007/s10875-026-01996-1. Online ahead of print. NO ABSTRACT PMID:41748971 | DOI:10.1007/s10875-026-01996-1
Journal of Clinical Immunology
A Cohort Study of 38 Classic Wiskott-Aldrich Syndrome Cases with Six Novel Mutations
J Clin Immunol. 2026 Feb 20. doi: 10.1007/s10875-026-01986-3. Online ahead of print. NO ABSTRACT PMID:41718912 | DOI:10.1007/s10875-026-01986-3
TFRC Germline Variants and Inborn Error of Immunity: Mechanistic Insights into Iron-Immune Crosstalk
J Clin Immunol. 2026 Feb 20. doi: 10.1007/s10875-026-01999-y. Online ahead of print. NO ABSTRACT PMID:41714512 | DOI:10.1007/s10875-026-01999-y
Good’s Syndrome Mirrors a Combined Immunodeficiency with Anti-Cytokine Antibodies in the Total Absence of B Cells
J Clin Immunol. 2026 Feb 17. doi: 10.1007/s10875-026-01992-5. Online ahead of print. NO ABSTRACT PMID:41701387 | DOI:10.1007/s10875-026-01992-5
Spectrum of Primary Immune Regulatory Disorders in Children in a Highly Consanguineous Population: Report from a National Registry
J Clin Immunol. 2026 Feb 14. doi: 10.1007/s10875-026-01993-4. Online ahead of print. NO ABSTRACT PMID:41688586 | DOI:10.1007/s10875-026-01993-4
WAS Protein Deficiency Disrupts Memory B Cell Formation During Acute LCMV Infection
J Clin Immunol. 2026 Feb 11. doi: 10.1007/s10875-026-01984-5. Online ahead of print. ABSTRACT Wiskott-Aldrich syndrome (WAS) is a rare x-linked monogenic immunodeficiency disease, caused by the mutation of WAS gene encoding WAS protein (WASp). Previous findings in WAS patients show B cell perturbations in the periphery, characterized by diminished B-cell numbers and phenotype abnormalities, including … Read more
Transcatheter Arterial Approach for Refractory Liver Abscesses in Chronic Granulomatous Disease: A Case Series
J Clin Immunol. 2026 Feb 10;46(1):16. doi: 10.1007/s10875-025-01976-x. NO ABSTRACT PMID:41665758 | DOI:10.1007/s10875-025-01976-x
Pediatric IPEX-Associated Dermatitis Responds To Dupilumab: Evidence from Skin Transcriptomics and Immune Profiling
J Clin Immunol. 2026 Feb 7. doi: 10.1007/s10875-025-01979-8. Online ahead of print. ABSTRACT PURPOSE: Immunodysregulation, Polyendocrinopathy, Enteropathy, and X-linked (IPEX) syndrome is a rare autoimmune disorder caused by mutations in the FOXP3 gene. Patients with IPEX frequently present with severe dermatitis, diabetes, and enteropathy. This study explores the efficacy of Dupilumab (an anti-IL-4Rα monoclonal antibody) … Read more
αβT/CD19-depleted Allogeneic Stem Cell Transplantation in Adults with Inborn Errors of Immunity
J Clin Immunol. 2026 Feb 3. doi: 10.1007/s10875-025-01978-9. Online ahead of print. ABSTRACT PURPOSE: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is successful in pediatric patients with inborn errors of immunity (IEI), but its use in adults is complicated by pre-existing organ damage and increased risk of treatment-related mortality. Ex vivo graft engineering using αβTCR/CD19 depletion … Read more
Follicular Helper T Cells and B Cell Maturation in Patients with 22q11.2 Deletion Syndrome and Recurrent Infections
J Clin Immunol. 2026 Feb 3. doi: 10.1007/s10875-026-01987-2. Online ahead of print. ABSTRACT PURPOSE: 22q11.2 Deletion Syndrome has been primarily described as a disorder of T cell production secondary to thymic hypoplasia. However, there is great complexity in the clinical picture with infections, autoimmunity, and inflammation occurring. Emerging evidence suggests that qualitative T cell dysfunction … Read more