Multiple sclerosis, which affects around one in 500 people in Switzerland, is an autoimmune disease in which immune cells attack the central nervous system, causing irreversible damage. Current treatments involve blocking the immune system to prevent i…
Researchers at UMC Utrecht have discovered that converting monoclonal antibodies from the IgG to the IgM isotype can significantly broaden their ability to recognize and bind multiple human-relevant bacterial pathogens. The study is published in Cell R…
HIV remains a major global health issue, affecting nearly 40 million people worldwide. Current treatments, known as antiretroviral therapy (ART), are highly effective at suppressing the virus and preventing illness, but they are not curative and must b…
A study published in Cancer Discovery finds that combining an epigenetic therapy with an anti-PD-1 antibody, which uses the body’s natural response to viral infections, shows promising results in patients with relapsed or refractory natural killer/T-ce…
Researchers at Cincinnati Children’s Hospital Medical Center in collaboration with Roche, have developed a next-generation human liver organoid microarray platform that could help predict which drugs may cause harmful immune reactions in some people.
A tiny molecule called a nanobody may succeed where today’s cancer drugs often fail, according to University of Hawaiʻi at Mānoa researcher Stefan Moisyadi, who has been refining the concept for nearly a decade.
A special group of immune cells known as regulatory T cells, or Tregs for short, became an overnight sensation when a trio of U.S. and Japanese scientists won the Nobel Prize in physiology or medicine on Oct. 6, 2025, for their discovery and elucidatio…
Cedars-Sinai investigators have identified a “molecular switch” on a gene strongly associated with the autoimmune disease lupus, which appears to propel immune cells into overdrive, attacking and damaging healthy tissues and organs.
Many advanced cancers develop resistance to treatment and become highly aggressive, often leaving patients with limited treatment options. In some cancers, including lung, pancreatic and prostate tumors, a key driver of treatment resistance and metasta…
The aim of immunotherapy strategies is to leverage cells in the patient’s own immune system to destroy tumor cells. Using a preclinical model, scientists from the Institut Pasteur and Inserm successfully stimulated an effective anti-tumor immune respon…
