New research has found that delivering a stronger form of the tuberculosis vaccine directly to the lungs can help generate protective immune cells to help fight the disease. The research is published in the journal Mucosal Immunology.
A specially engineered antibody that can accurately deliver RNA treatments into hard-to-reach and hard-to-treat tumors significantly improved survival and reduced tumor sizes in animal models, according to a study reported in Science Translational Medi…
Blindness, pneumonia, severe diarrhea and even death—measles virus infections, especially in children, can have devastating consequences. Fortunately, we have a safe and effective defense. Measles vaccines are estimated to have averted more than 60 mil…
Cells and tissues surrounding a breast cancer tumor may hold critical information about how patients will respond to treatment, according to a new study from Johns Hopkins University.
mRNA bundled in lipid nanoparticles trains T cells in mice to eliminate cancer. Coupled with noninvasive imaging, researchers tracked the in situ CAR-T cells to assess their effectiveness and safety.
Immunotherapy using CAR T cells is finding ever more applications. In addition to their use in the treatment of blood and lymphatic cancers, CAR T cells are now also being investigated for solid tumors and various autoimmune diseases. With the growing …
Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs. Approximately 12 new cases of this extreme…
The National Cancer Center Research Institute in Tokyo reports that a newly isolated gut bacterium, designated Hominenteromicrobium strain YB328, mobilizes specialized dendritic cells to strengthen the impact of PD-1 blockade immunotherapy across sever…
High dietary inflammatory index (DII), which quantifies the inflammatory potential of diet, is associated with increased prevalence of atopic dermatitis (AD), according to a study published online June 19 in Frontiers of Immunology.
As cancer cases have increased worldwide, the disease has become more complex, presenting challenges to scientific advances in diagnosis and treatment. In this context, artificial intelligence (AI) has emerged as a valuable tool for predicting and dete…
