Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated a remarkable ability t…
A new study in the journal Human Gene Therapy showed that more than half of individuals with Niemann-Pick disease, type C1 (NPC1) who were tested lacked neutralizing antibodies against either adeno-associated virus (AAV) 2 or AAV9.
Researchers at the University of Colorado Anschutz Medical Campus have successfully developed a supercharged iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the cells, particularly against cancer cells that are harde…
New research from RCSI University of Medicine and Health Sciences has found that white blood cells which ‘remember’ past inflammatory events are quick to overreact, raising the risk of blood clots.
Preterm babies are fragile. This is especially true for infants born just six to seven months into a pregnancy. Called extremely preterm infants, these children essentially finish developing outside the uterus. Studying this vulnerable population is ch…
Researchers from the University of Chicago Medicine Comprehensive Cancer Center have demonstrated the potential of a novel treatment approach including immunotherapy to treat advanced human papillomavirus (HPV)-negative head and neck squamous cell carc…
Hepatocellular carcinoma (HCC) represents about 80 to 90% of cases of primary liver cancer. On a global level, 905,700 new cases and 830,200 deaths were registered in 2020, according to the World Health Organization. In Switzerland, the Statistics Offi…
Two new studies led by researchers at Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma—a rare and often devastating autoimmune disease that causes fibrosis (tissue hardening) a…
For more than three decades, scientists have been racing to stop Alzheimer’s disease by removing amyloid beta plaques—sticky clumps of toxic protein that accumulate in the brain.
The U.S. Food and Drug Administration has expanded its indication of ALK’s Odactra, a house dust mite allergen tablet, for the treatment of house dust mite-induced allergic rhinitis, with or without conjunctivitis, to include children ages 5 through 11…
