Within a large group of more than 700 patients treated with CAR T cell therapy, researchers found no evidence that the therapy itself caused any type of secondary cancer in the modified T cells, according to new analysis reported today in Nature Medici…
Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now discovered that CAR molecules can be transferred from the CAR-T cells to other T cells in the tumor microenvironment.
Mayo Clinic researchers have identified a targeted therapy that could bring relief to people living with lichen planus, a chronic inflammatory skin condition of the skin, hair, nails, mouth and genitals. They described their findings in a study publish…
Imagine a bustling metropolis within your mouth—a dynamic community of microorganisms forming biofilms on your teeth and gums. This oral microbiome is not only essential for maintaining oral health, but also plays a pivotal role in shaping your immune …
Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune check…
Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders—T cells—lose their ability to function effectively. Research, led by the Peter Doherty Institute for Infection …
A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will respond to new therapies. The research, published in Clinical Cancer Research, found that measuring the interaction between two…
A team of international researchers led by scientists at City of Hope have demonstrated a way to boost thymic function after damage in preclinical studies. The team’s study results, published today in the journal Immunity, outline their discovery of a …
A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of β-glucans. These are natural sugar compounds found in bacteria, fungi and grains. The results indicate that β-glucans can targe…
Psoriasis, a painful and uncomfortable inflammatory skin condition that affects millions worldwide, flares up from the activity of disease- and infection-protecting immune cells.
