Scientists at Pohang University of Science and Technology (POSTECH) and ShanghaiTech University have achieved a breakthrough in cancer immunotherapy research. Led by Professors Sin-Hyeog Im and Dipayan Rudra, the research team, with Dr. Amit Sharma as …
T helper (TH) cells are essential immune cells that help other immune cells function effectively. When activated in response to environmental stimuli, these cells can differentiate into either TH1 cells, which fight against viruses and intracellular pa…
Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells are too varied, and the microenvironment is too tumor-friendly. Researchers…
A research team led by UCLA Health Jonsson Comprehensive Cancer Center investigators has shown that combining pembrolizumab, an immunotherapy drug, with standard chemotherapy can improve treatment outcomes for patients with small cell bladder cancer an…
Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, and what is the relationship between the scale and nature of this activatio…
The largest ever clinical trial of T cell therapy for solid tumors has ended, heralding a new era for precision T cell therapy. Led by a Singapore clinician-scientist, the multinational, Phase III VANCE trial demonstrates that Singapore has the experti…
Researchers at Uppsala University and KTH Royal Institute of Technology have developed a new form of precision medicine, an antibody, with the potential to treat several types of cancer. Researchers have managed to combine three different functions in …
After viruses infected our evolutionary ancestors, bits of viral DNA lodged themselves into their genomes—and we still carry around genetic remnants of those viruses now. Known as endogenous retroviruses, these pieces of ancient invaders aren’t able to…
The process of identifying promising small molecule drug candidates that target cancer checkpoints may become faster and smarter through virtual screening, according to Weill Cornell Medicine researchers.
University of Kentucky Markey Cancer Center researchers identified a protein that could be key to developing new treatments for triple-negative breast cancer.
