Trends Immunol. 2026 Aug 27:S1471-4906(26)00226-7. doi: 10.1016/j.it.2026.08.010. Online ahead of print.
ABSTRACT
Most individuals infected with Mycobacterium tuberculosis never develop active disease, yet the airway immune events determining outcome remain poorly understood. Branchett and colleagues prospectively profiled bronchoalveolar lavage from recent tuberculosis contacts, revealing that progression reflects a dynamic competition between opposing local immune states rather than a single immunological failure.
PMID:42660718 | DOI:10.1016/j.it.2026.08.010