Tracking tumor and immune remodeling through myeloma therapy. Jian Cui

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Trends Immunol. 2026 Sep 1:S1471-4906(26)00220-6. doi: 10.1016/j.it.2026.08.004. Online ahead of print.

ABSTRACT

Multiple myeloma remains incurable despite therapeutic advances. Longitudinal profiling of bone marrow and peripheral blood by Chander et al. reveals selective persistence of malignant plasma cell states, compartment-specific immune remodeling, incomplete humoral recovery after autologous stem cell transplantation, and divergent vaccine responses.

PMID:42680673 | DOI:10.1016/j.it.2026.08.004

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