Weapon of choice: viruses share cross-kingdom tools. C J E Metcalf

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Trends Immunol. 2024 Nov 21:S1471-4906(24)00277-1. doi: 10.1016/j.it.2024.11.006. Online ahead of print.

ABSTRACT

Following on from the discovery that innate immune pathways are shared widely across the tree of life comes another surprise: Hobbs et al. show that viruses targeting animals and bacteria also use highly conserved tools to fight back. Why such mechanisms remain seemingly unchanged despite the rapid coevolution among hosts and pathogens is now a key open question for the field.

PMID:39578118 | DOI:10.1016/j.it.2024.11.006

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