J Immunol. 2025 Jun 9:vkaf115. doi: 10.1093/jimmun/vkaf115. Online ahead of print.
ABSTRACT
This Pillars of Immunology article revisits the landmark 2007 study by Foster, Hargreaves, and Medzhitov-the first to uncover the mechanistic basis of memory in the innate immune system. This pivotal study marks a fundamental shift in our understanding of innate immunity, revealing an epigenetic logic that enables immune memory beyond the adaptive immune system.
PMID:40489770 | DOI:10.1093/jimmun/vkaf115