Comparative Analysis of the TCR Repertoire in Bone Marrow CD8+ T Cells From Patients With Acute Myeloid Leukemia, Myelodysplastic Neoplasms, and Chronic Myelomonocytic Leukemia. [[{“value”:”Kyriaki Katsiki,
Athanasios Tasis,
Anastasia Filia,
Ioannis Kotsianidis,
Ioannis Mitroulis”}]]
Bone marrow CD8+ T cells from patients with MDS and CMML show decreased TCR diversity compared to AML. Treatment with the hypomethylating agent azacitidine in MDS and CMML alters TCR repertoire of CD8+ T cells without affecting TCR diversity.
