A physiological perspective on neuroimmune tissue innervation. Daniel A Waizman

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Trends Immunol. 2025 Jun 11:S1471-4906(25)00124-3. doi: 10.1016/j.it.2025.05.003. Online ahead of print.

ABSTRACT

Organisms must adapt to unpredictable environmental perturbations. We propose that the immune system, which can be redistributed across tissues (‘immune innervation’), cooperates with the nervous system to form a larger integrative network that can maximize the number of adaptive physiologic states to a given perturbation.

PMID:40506286 | DOI:10.1016/j.it.2025.05.003

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