Trends Immunol. 2025 Aug 26:S1471-4906(25)00200-5. doi: 10.1016/j.it.2025.08.002. Online ahead of print.
ABSTRACT
Gut dysbiosis and intestinal inflammation may contribute to neurological disorders through the gut-brain axis. A recent report by White et al. uncovered that intestinal inflammation triggers the migration of microbiota-specific CD4+ T cells to the brain, where they drive neuroinflammatory responses via IL-23R/GM-CSF.
PMID:40866136 | DOI:10.1016/j.it.2025.08.002