Kupffer cells facilitate intrahepatic CD4 T cell help. Tobias Boettler

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Trends Immunol. 2025 Sep 29:S1471-4906(25)00223-6. doi: 10.1016/j.it.2025.09.004. Online ahead of print.

ABSTRACT

Intrahepatic immune responses are often insufficient to control hepatitis virus infections. A recent study by Venzin and colleagues demonstrates a detailed mechanism by which an intrahepatic tricellular network and the cytokine IL-27 can augment virus-specific immunity.

PMID:41027760 | DOI:10.1016/j.it.2025.09.004

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