Trends Immunol. 2026 Mar 5:S1471-4906(26)00017-7. doi: 10.1016/j.it.2026.02.002. Online ahead of print.
ABSTRACT
De Leeuw et al. conducted human observational and murine studies to establish the combined role of parental aeroallergen sensitization and early-life respiratory syncytial virus infection in asthma development. The findings reveal synergistic effects driving immunological, pathological, and physiological changes resembling asthma, advancing the understanding of disease mechanisms and potential preventive targets.
PMID:41792009 | DOI:10.1016/j.it.2026.02.002