Specialty care remains out of reach for many children with uncontrolled asthma
Historically, marginalized children would benefit from better connection to specialists
Allergy and immunology
Active aldehydes drive T cell exhaustion in the tumor microenvironment, finds study
Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment involves CD8⁺ T cells, also known as killer T cells, which play a crucial role in attacking tumors. Unfortunately, these cells grad…
Dual gene deletion reveals potential biomarkers for predicting immunotherapy success
The deletion of two cancer genes, CHD1 and MAP3K7, improves how well tumors respond to cancer immunotherapy and could be used as biomarkers to help predict which patients are most likely to benefit from treatment, new research shows.
B cells play a more sinister role than believed in progression of type 1 diabetes
A recent study by Vanderbilt Health researchers has revealed a greater, detrimental role for B lymphocytes (B cells) in the progression of type 1 diabetes (T1D).
Certain antibiotics may may boost immune system
Research led by Lancaster University has discovered that a class of antibiotics—fluoroquinolones—can directly alter the potential bacterial killing ability of one of our immune cells called the macrophage.
Study links stroke-induced stress response to weakened immune system and higher infection risk
A new University of Manchester and Edinburgh study published in the journal Brain, Behavior and Immunity has found that people who have had a stroke have fewer of a specific type of immune cell called B cells, which normally produce antibodies to fight…
Pan-fungal vaccine proves effective against Candida auris in mice
A vaccine created by University of Georgia researchers to battle multiple life-threatening fungal infections is also effective against Candida auris in mice, according to a new study published in Vaccines by researchers in the UGA Center for Vaccines a…
Can training your brain boost immune response? Vaccination study highlights power of positive thinking
Training people to activate a part of the brain linked to reward and positive expectations may be associated with an increase in the body’s immune response to a vaccine. The findings from a study involving 85 participants, published in Nature Medicine,…
Small molecules could treat Crohn’s disease by mimicking a protective gene variant
An estimated 3 million Americans have an inflammatory bowel disease (IBD) such as Crohn’s disease or ulcerative colitis. But a lucky few individuals are far less likely to develop IBD because they have a rare variant of a gene called CARD9. This protec…
Federal officials scale back childhood vaccination schedule in historic move
A decision by federal officials to scale back the number of vaccines recommended for children surprised some Northeastern University public health experts, who warn the move could confuse parents and increase the risk of preventable diseases.