Chen, Y., Liu, X., Chen, J., Kuang, L., Zhang, N., Li, D., Zhao, D., Xue, D., Lei, J., Zhang, J., Li, Y., Wu, L.

Macrophage CCL7 promotes resistance to immunotherapy for colorectal cancer by regulating the infiltration of macrophages and CD8+ T cells

25 de November de 2025 by Chen, Y., Liu, X., Chen, J., Kuang, L., Zhang, N., Li, D., Zhao, D., Xue, D., Lei, J., Zhang, J., Li, Y., Wu, L.

Background
Immune checkpoint inhibitors (ICIs) have been proven to be one of the most promising and effective immunotherapies; however, their efficacy in colorectal cancer (CRC) remains significantly limited. Therefore, understanding the mechanism of …