SARS-CoV-2 evolution enhances endocytic uptake while preserving TMPRSS2-dependent fusion
BackgroundOf the five SARS-CoV-2 variants-of-concern (VOC), Omicron shows increased transmissibility and infectivity, but lower pathogenicity. This drop in virulence was associated with an altered entry of VOC Omicron into airway epithelia by endocytos…