Dong, Y., Zhang, Z., Luan, S., Zheng, M., Wang, Z., Chen, Y., Chen, X., Tong, A., Yang, H.

Novel bispecific antibody-drug conjugate targeting PD-L1 and B7-H3 enhances antitumor efficacy and promotes immune-mediated antitumor responses

2 de October de 2024 by Dong, Y., Zhang, Z., Luan, S., Zheng, M., Wang, Z., Chen, Y., Chen, X., Tong, A., Yang, H.

Background
Antibody-drug conjugates (ADCs) offer a promising approach, combining monoclonal antibodies with chemotherapeutic drugs to target cancer cells effectively while minimizing toxicity.

Methods
This study examined the therapeutic efficacy and …