Duan, J., Chen, T., Li, Q., Zhang, Y., Lu, T., Xue, J., Sun, Y., Gao, L., Zhang, Y.

Protein arginine methyltransferase 6 enhances immune checkpoint blockade efficacy via the STING pathway in MMR-proficient colorectal cancer

14 de March de 2025 by Duan, J., Chen, T., Li, Q., Zhang, Y., Lu, T., Xue, J., Sun, Y., Gao, L., Zhang, Y.

Background
The emergence of immunotherapy has revolutionized the paradigm of cancer treatment with immune checkpoint blockades (ICB) in solid cancers, including colorectal cancer (CRC). However, only a small subset of CRC patients harboring deficient …