IRAK3 is upregulated in rheumatoid arthritis synovium and delays the onset of experimental arthritis
Tumour necrosis factor (TNF) is a potent inducer of endotoxin tolerance-associated molecules, such as interleukin-1 receptor-associated kinase 3 (IRAK3), and also a therapeutic target in inflammatory autoimmune diseases, as it upregulates the productio…