Hou, Z., Lu, F., Lin, J., Wu, Y., Chen, L., Fang, H., Chen, L., Zhang, S., Huang, H., Pan, Y.

Loss of Annexin A1 in macrophages restrains efferocytosis and remodels immune microenvironment in pancreatic cancer by activating the cGAS/STING pathway

5 de September de 2024 by Hou, Z., Lu, F., Lin, J., Wu, Y., Chen, L., Fang, H., Chen, L., Zhang, S., Huang, H., Pan, Y.

Objective
Pancreatic cancer is an incurable malignant disease with extremely poor prognosis and a complex tumor microenvironment. We sought to characterize the role of Annexin A1 (ANXA1) in pancreatic cancer, including its ability to promote efferocyt…