Hu, S., Xu, J., Wang, Z., Zhang, Y., Zhao, C., Liu, Y., Luo, F., Cheng, P., Wang, J., Zhao, J.

SAMHD1 drives immunosuppression in non-small cell lung cancer by promoting macrophage infiltration and restricting oncolytic adenovirus replication

29 de January de 2026 by Hu, S., Xu, J., Wang, Z., Zhang, Y., Zhao, C., Liu, Y., Luo, F., Cheng, P., Wang, J., Zhao, J.

Background
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and the leading cause of cancer-related deaths. Immune checkpoint inhibitors (ICIs) of programmed death-1 (PD-1)/programmed death ligand-1 signaling induce tumor regr…