Siglec-7 inhibits TLR3-induced pro-inflammatory cytokine production from human monocytes and macrophages
Immune checkpoint receptors, including Sialic-acid-binding immunoglobulin-like lectins (Siglecs), are critical regulators of immune homeostasis. Siglecs can serve as negative regulators of Toll-like receptor (TLR) signaling, promoting the resolution of…