Liang, X., Li, J., Chen, J., Chen, C., Li, H., Yan, C., Guo, C., Han, Y., Liu, W., Sai, K., Lin, Y., Yan, G., Zhu, W., Liu, Y.

TAMs-mediated resistance to oncolytic virus M1 in solid tumors

14 de November de 2025 by Liang, X., Li, J., Chen, J., Chen, C., Li, H., Yan, C., Guo, C., Han, Y., Liu, W., Sai, K., Lin, Y., Yan, G., Zhu, W., Liu, Y.

Background
Oncolytic virus M1 (OVM), a naturally occurring alphavirus, has demonstrated potent antitumor activity in various solid tumor models by inducing immunogenic cell death and activating CD8+ T cells. However, its in vivo efficacy varies widely…

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