Lin, P., Wen, Y., Zhao, J., Zhang, F., Su, Y., He, H., Yu, H., Li, Q., Liu, C., Hu, Z., Li, Y., Fang, Z., Liang, L., Huang, S.

Decoding neoantigen-encoding tumor-specific transcripts unveils a shared target reservoir for immunotherapy in hepatocellular carcinoma

21 de July de 2026 by Lin, P., Wen, Y., Zhao, J., Zhang, F., Su, Y., He, H., Yu, H., Li, Q., Liu, C., Hu, Z., Li, Y., Fang, Z., Liang, L., Huang, S.

Background
Primary liver cancer, predominantly hepatocellular carcinoma (HCC), has limited therapeutic options. While mutation-derived neoantigen vaccine holds promise, its success is hindered by low antigen availability. This study explores transcrip…