Liu, Y., Ma, J., Ma, Y., Wang, B.-z., Wang, Y., Yuan, J., Zhang, F., Zhao, X., Chen, K., Zhang, X., Wang, H.

Neutrophil extracellular traps impede cancer metastatic seeding via protease-activated receptor 2-mediated downregulation of phagocytic checkpoint CD24

26 de February de 2025 by Liu, Y., Ma, J., Ma, Y., Wang, B.-z., Wang, Y., Yuan, J., Zhang, F., Zhao, X., Chen, K., Zhang, X., Wang, H.

Background
Phagocytic clearance by macrophages represents a critical immune surveillance mechanism in cancer liver metastasis. Neutrophils, the most abundant immune cells encountered by cancer cells in circulation, play key roles in metastasis through…