Lucy Bird Nature Reviews Immunology, Published online: 02 January 2025; doi:10.1038/s41577-024-01127-0Stress-induced gut leakage and immune activation lead to the release of IL-22, which acts directly on septal neurons in the brain to dampen the…
Nature Reviews Immunology, Published online: 29 November 2024; doi:10.1038/s41577-024-01120-7Sialylated IgG protects against severe influenza by inducing the transcriptional repressor REST, which dampens the inflammatory response and p…
Nature Reviews Immunology, Published online: 11 October 2024; doi:10.1038/s41577-024-01101-wFebrile temperatures disrupt metabolism and induce DNA damage disproportionately in T helper 1 cell subsets. Cells that survive apoptosis and a…
Nature Reviews Immunology, Published online: 29 July 2024; doi:10.1038/s41577-024-01072-yTransient depletion of the gut microbiome by antibiotics in early life reduces systemic levels of the metabolite indole-3-propionic acid, which ca…
Nature Reviews Immunology, Published online: 12 July 2024; doi:10.1038/s41577-024-01065-xAge-associated defects in dendritic cells can be corrected by hyperactivating adjuvants containing an oxidized phospholipid to induce effective an…
Nature Reviews Immunology, Published online: 31 May 2024; doi:10.1038/s41577-024-01053-1CD8+ T cells become exhausted when exposed to the mechanical forces of stiff solid tumours, owing to signalling through the transcription factor OSR2.
Nature Reviews Immunology, Published online: 24 April 2024; doi:10.1038/s41577-024-01036-2Sex hormones in male mice negatively regulate type 2 innate lymphoid cells in the skin, impairing the induction and activation of dendritic cells…
