Local T<sub>reg</sub> cell loss reprogrammes systemic antitumour immunity without breaking tolerance
Nature Reviews Immunology, Published online: 26 November 2025; doi:10.1038/s41577-025-01253-3A preprint by Bockman et al. reports a cDC2-CD4+ T cell axis that mediates local tumour control after ablation of intratumoral Treg cells, wit…