Moseman, J. E., Rastogi, I., Jeon, D., McNeel, D. G.

PD-1 blockade employed at the time CD8+ T cells are activated enhances their antitumor efficacy

8 de May de 2025 by Moseman, J. E., Rastogi, I., Jeon, D., McNeel, D. G.

Background
We have previously shown that immune checkpoint receptors, including PD-1, are upregulated on T cells at the time of their activation, and that blockade of these receptors can improve the efficacy of antitumor vaccines. In the present study…