Murphy, S. A., Li, J., Sahu, U., Swanner, J., Lewis, C. T., Anchang, B., Cui, Y., Chiocca, E. A., Kaur, B.

CD73 blockade enhances antitumor efficacy of oHSV in solid tumors by increasing macrophage-mediated antigen presentation

8 de January de 2026 by Murphy, S. A., Li, J., Sahu, U., Swanner, J., Lewis, C. T., Anchang, B., Cui, Y., Chiocca, E. A., Kaur, B.

Background
Oncolytic herpes simplex virus (oHSV) therapy is a live virus-based immunotherapy that lyses tumor cells which release antigens and activate antitumor immunity. oHSV therapy has been shown to increase ATP production and release of extracell…

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