Sun, Z., Xu, Y., Shao, B., Dang, P., Hu, S., Sun, H., Chen, C., Wang, C., Liu, J., Liu, Y., Hu, J.

Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model

23 de May de 2024 by Sun, Z., Xu, Y., Shao, B., Dang, P., Hu, S., Sun, H., Chen, C., Wang, C., Liu, J., Liu, Y., Hu, J.

Background
Accumulating evidence demonstrates that an increased tumor-associated macrophage abundance is often associated with poor prognosis in colorectal cancer (CRC). The mechanism underlying the effect of tumor-derived exosomes on M2 macrophage po…