Wan, L., Li, B., Ma, T., Wang, M., Xie, F., Ge, H., Xiao, Z., Chen, X., Meng, L., Zhang, L., Xie, K., Wang, Q.

An Immune-privileged niche mediates immunotherapy resistance in esophageal carcinoma

15 de January de 2026 by Wan, L., Li, B., Ma, T., Wang, M., Xie, F., Ge, H., Xiao, Z., Chen, X., Meng, L., Zhang, L., Xie, K., Wang, Q.

Background
Neoadjuvant immunotherapy has reshaped the treatment paradigm for esophageal squamous cell carcinoma (ESCC), yet mechanisms of resistance in non-responders remain poorly understood. Specifically, the spatial orchestration of the tumor micro…