Xie, H., Zhang, K., Yin, H., Zhang, S., Pan, S., Wu, R., Han, Y., Xu, Y., Jiang, W., You, B.

Acetyltransferase NAT10 inhibits T-cell immunity and promotes nasopharyngeal carcinoma progression through DDX5/HMGB1 axis

12 de February de 2025 by Xie, H., Zhang, K., Yin, H., Zhang, S., Pan, S., Wu, R., Han, Y., Xu, Y., Jiang, W., You, B.

Background
Immunosuppression significantly contributes to treatment failure in nasopharyngeal carcinoma (NPC). Messenger RNA (mRNA) modifications such as methylation and acetylation play crucial roles in immunosuppression. However, N4-acetylcytidine (…