Zhang, H., Xu, K., Zhen, L., Jiang, Y., Chou, A., Chen, M., Chen, Y., Wu, J., Mao, W.

SPP1+ macrophage-induced CD74+ tumor cells promote adrenocortical carcinoma tumor thrombus via the SPP1/CD44/JAK/STAT signaling

23 de September de 2026 by Zhang, H., Xu, K., Zhen, L., Jiang, Y., Chou, A., Chen, M., Chen, Y., Wu, J., Mao, W.

Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine malignancy with limited treatment options and poor prognosis. Venous tumor thrombus (VTT) is a common complication associated with ACC progression, yet the cellular and molecular…