Zhong, Y., Wang, Y., Wang, C., Cao, K., Wang, X., Xu, X., Yang, M., Zhang, G., Liu, H., Lu, J.

Targeting mesothelin-CD24 axis repolarizes tumor-associated macrophages to potentiate PD-1 blockade therapy in high-grade serous ovarian cancer

26 de February de 2025 by Zhong, Y., Wang, Y., Wang, C., Cao, K., Wang, X., Xu, X., Yang, M., Zhang, G., Liu, H., Lu, J.

Background
High-grade serous ovarian cancer (HGSOC) is a highly aggressive malignancy marked by an immunosuppressive tumor microenvironment that hinders effective immune responses. A key feature of this environment is the extensive infiltration of mye…