Zhou, Y., Liu, Z., Kaysar, P., Han, Y., Ma, Y., Yu, X., Ni, B., Chen, Z., Xie, Y., Zhang, H., Li, Y.

HIF1A+CSF3R+ neutrophils-dominated hypoxic niche induced metabolic reprogramming for neoadjuvant therapy resistance in NSCLC

8 de September de 2026 by Zhou, Y., Liu, Z., Kaysar, P., Han, Y., Ma, Y., Yu, X., Ni, B., Chen, Z., Xie, Y., Zhang, H., Li, Y.

Background
Non-small cell lung cancer (NSCLC) is one of the frequently occurring cancers characterized by molecular heterogeneity and multiple immune cell infiltration patterns, which are associated with treatment sensitivity and resistance. However, …