Zhu, H., Ge, F., Dai, J., Yang, S., Yuan, T., Zheng, C., Dong, X., Hu, R., Zhou, T., He, Q., Yang, B., Zhu, H.

Targeting VCP enhances colorectal cancer therapy through STING stabilization

19 de November de 2025 by Zhu, H., Ge, F., Dai, J., Yang, S., Yuan, T., Zheng, C., Dong, X., Hu, R., Zhou, T., He, Q., Yang, B., Zhu, H.

Background
Immunotherapy resistance in microsatellite-stable colorectal cancer (CRC) remains a major therapeutic challenge. Recent strategies to overcome the immunosuppressive tumor microenvironment have focused on reactivating innate immune pathways,…