New insights on celery allergies and associated risks
Celery, a major cause of vegetable allergies, carries the risk of causing severe allergic reactions, especially in individuals with mugwort pollen sensitization.
Medical Xpress
Inhibiting a metabolic pathway provides new approach to Epstein-Barr virus and resulting diseases
The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease, …
Tracking down the genetic causes of lupus to personalize treatment
Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient’s immune system—a therapy that has its own serious risks.
Tumor mutations may not predict response to immunotherapy, study finds
The number of mutations in the DNA of cancerous tumors may not be an indicator of how well patients will respond to immune checkpoint inhibitors (ICIs), a commonly prescribed type of immunotherapy, a team led by UT Southwestern Medical Center researche…
Study sheds light on the origin of eosinophils and effects of current precision therapies
Eosinophils are specialized cells of our immune system. They are identified by their distinctive granules that stain red when treated with an acidic reagent, eosin, that gave them their name. Eosinophils are typically rare in our blood and tissues, acc…
CAR T cell therapy for pediatric brain cancer warrants further study
Novel therapeutic approaches are needed for children with diffuse midline glioma (DMG) and other recurrent high-grade central nervous system (CNS) tumors, aggressive brain cancers with poor prognoses. A type of immunotherapy using T cells modified with…
Researchers explore present and future treatment options for hepatocellular carcinoma using immunotherapy
Hepatocellular carcinoma (HCC), a prevalent form of cancer, profoundly influences the progression and prognosis of the disease through immune response mechanisms. The tumor microenvironment plays a pivotal role in fostering immune suppression and maint…
Researchers determine mechanism of action of delta inulin, uncover key to more effective vaccines
Researchers from the Centenary Institute and the University of Sydney have made a major discovery in vaccine science, gaining new insights into delta inulin as a crucial vaccine component. Their findings offer a promising pathway for advancing the next…
Immune-checkpoint inhibitors protect bone by promoting osteogenesis, exploratory study shows
Immune checkpoint inhibitors (ICIs), widely employed anticancer agents, have been found to impact bone turnover, potentially conferring a protective effect on bone through the promotion of osteogenesis. These surprising findings stem from a recent stud…
Urban gardening may improve human health—research subjects benefit from microbial exposure
A collaborative study between the University of Helsinki, Natural Resources Institute Finland and Tampere University demonstrated that a one-month indoor gardening period increased the bacterial diversity of the skin and was associated with higher leve…